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Anti-parasitic Drugs
Ivermectin

This medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, & enterobiasis.

Dapsone

sulfone drug used to treat acne vulgaris, Hansen’s disease, and dermatitis herpetiformis.

Mefloquine

antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.

Quinine

alkaloid used to treat uncomplicated Plasmodium falciparum malaria.

Albendazole

benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections.

Amodiaquine

antimalarial drug.

Mebendazole

benzimidazole anthelmintic used to treat helminth infections.

Amphotericin B

anti-fungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.

Thiabendazole

benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.

Levamisole

Levamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections.

Tinidazole

nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.

Praziquantel

anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis.

Oxamniquine

For treatment of Schistosomiasis caused by Schistosoma mansoni

Proguanil

medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.

Posaconazole

triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.

Paromomycin

amino-glycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.

Sinefungin

Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include…

Fumagillin

Fumagillin is a complex biomolecule and used as an antimicrobial agent. It was isolated in 1949 from the microbial organism Aspergillus fumigatus.

Diminazene

Diminazene, also known as Diminazine, 4,4′-(Diazoamino)benzamidine, 4,4′-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin.

Salicylhydroxamic Acid

Salicylhydroxamic acid is a drug that is a potent and irreversible enzyme inhibitor of the urease enzyme in various bacteria and plants; it is usually used for urinary tract infections.

Pyrimethamine

This drug used in the prevention and treatment of toxoplasmosis and malaria.

Doxycycline

tetracycline antibiotic used to treat a wide variety of bacterial infections.

Sulfadiazine

sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.

Nitazoxanide

Thiazolide anti-infective used to treat infections by protozoa, helminths, anaerobic bacteria, microaerophilic bacteria, and viruses.

Piperazine

medication used to treat roundworm and pinworm.

Furazolidone

drug for the treatment of infectious diarrhea.

Sulfametopyrazine

antibiotic used in the treatment or prevention of bacterial infections and malaria.

Diethylcarbamazine

anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa.

Pentamidine

antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.

Quinidine

medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.

Metronidazole

nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.

Primaquine

antimalarial indicated to prevent relapse of vivax malaria.

Atovaquone

antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.

Halofantrine

antimalarial used for the treatment of severe malaria.

Sulfadoxine

long acting sulphonamide used for the treatment or prevention of malaria.

Hydroxychloroquine

antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.

5'-S-methyl-5'-thioadenosine

It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It derives from an adenosine

Benzimidazole

Benzimidazole is a heterocyclic aromatic organic compound. This bicyclic compound may be viewed as fused rings of the aromatic compounds benzene and imidazole. It is a colorless solid.

Radicicol

Radicicol, also known as monorden, is a natural product that binds to Hsp90 and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis.

Geneticin

Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both…

Anti-parasitic Drugs
Bithionol

Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders

Oxibendazole

Investigated for use/treatment in infectious and parasitic disease (unspecified) and pediatric indications.

Andrographolide

Investigated for use/treatment in ulcerative colitis.

Eflornithine

A medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin.

Tafenoquine

An antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.

Niclosamide

anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.

Anisomycin

Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.

Diloxanide

Diloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially

Miltefosine

antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type

Diiodohydroxyquinoline

Used in the treatment of amoebiasis.

Pyrantel

anthelmintic used to treat helminth infections.

Cambendazole

veterinary anti-parasitic drug

Coumaphos

fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature.

Dichlorophen

Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm

Diclazuril

Diclazuril is a coccidiostat.

Eprinomectin

Eprinomectin is an avermectin used as a veterinary topical endectocide.

Fenbendazole

Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms

Monensin

Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.

Narasin

Narasin is an agent with coccidiostat and antibacterial properties.

Phenothiazine

Phenothiazine (PTZ) is an organic thiazine compound.

Halofuginone

For the treatment of scleroderma, cancer, and restenosis.

Doxycycline

Intended for use as a radiation sensitizer in the treatment of brain cancer.

Spiramycin

A macrolide antimicrobial agent used in the treatment of various bacterial infections.

Lonidamine

Investigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors

Lumefantrine

An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.

Pyrvinium

anthelmintic agent used for the treatment of pinworm infestations.

Puromycin

Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting.

Flubendazole

Flubendazole is an anthelmintic that is used to treat worm infection in humans

Chlortetracycline

first tetracycline antibiotic most commonly used for veterinary purposes

Artesunate

Artesunate is an artemisinin derivative indicated for the initial treatment of severe malaria.

Hexylresorcinol

ingredient used to relieve irritation, pain, and prevent infection.

Amprolium

Amprolium is a coccidiostat used in poultry.

Clorsulon

The treatment and control of adult liver flukes

Decoquinate

Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.

Dichlorvos

Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products

Doramectin

Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice

Febantel

Febantel is a broad-spectrum antiparasitic active ingredient used in veterinary medicine in pets and livestock against internal parasites (roundworms, tapeworms).

Lasalocid

Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of Streptomyces lasaliensis.

Moxidectin

Moxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus

Nicarbazin

Nicarbazin is a coccidiostat used on meat chickens. It is also used as a contraceptive for population control of Canada geese and feral pigeons.

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